Diagnostic evaluation may include: Detailed neurological examination assessing sensation, reflexes, and motor function Hemoglobin A1c measurement to evaluate recent glycemic control Vitamin B12 levels and methylmalonic acid (if B12 is borderline) Serum protein electrophoresis (SPEP) and immunofixation to screen for paraproteinemia Thyroid function tests, as hypothyroidism can contribute to neuropathic symptoms Comprehensive metabolic panel to assess renal and hepatic function Nerve conduction studies in selected cases with atypical features Management strategies focus on optimizing glycemic control, which remains the most evidence-based intervention for preventing and potentially improving diabetic neuropathy
Olivia MF, Michail S, Michael AT, Fadime D, Bindiya T, Sahin-Efe Ayse, et al
The way semaglutide works supports the idea that it is meant for long-term use
Researchers have observed that patients prescribed semaglutide, the active ingredient in both drugs, had an increased risk of nonarteritic anterior ischemic optic neuropathy (NAION)
